Bone-marrow and Stromal Niches that Maintain Immune Memory

immunology-aging-memory open composite 65%
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Composite
65%
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Priority
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Importance
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Tractability
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Market price
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Description

Determine whether memory failure reflects niche loss, altered cytokine tone, or changed trafficking into survival compartments. Boundary domains: stromal-biology, humoral-immunity. Representative papers: The aging bone marrow and its impact on immune responses in old age.; Dynamic organization of the bone marrow plasma cell niche.; Impact of niche aging on thymic regeneration and immune reconstitution.

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