What determines organelle-specific autophagy selectivity in neurodegenerative disease contexts?

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Description

The review covers various organelle-specific autophagy types but doesn’t address what molecular mechanisms determine which organelles are selectively targeted for autophagy in neurodegeneration. This selectivity mechanism is crucial for understanding disease progression and therapeutic intervention.

Gap type: open_question Source paper: Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles. (2021, Autophagy, PMID:32048886)

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