Are tau-MAP6 interactions disrupted in tauopathies and other neurodegenerative diseases?

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Description

The study establishes the importance of tau-MAP6 balance in normal neuronal development, but whether this balance is altered in disease states remains unexplored. Disruption of this antagonistic relationship could contribute to neurodegeneration pathogenesis.

Gap type: open_question Source paper: Antagonistic roles of tau and MAP6 in regulating neuronal development. (2024, J Cell Sci, PMID:39257379)

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