How does Reelin trigger recognition-adhesion among target neurons to form architectonic patterns?

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Description

The abstract states that Reelin is required for proper neuronal lamination and pattern formation, but explicitly notes that ‘the action of Reelin is unknown.’ Understanding this mechanism is critical since defective Reelin signaling causes human lissencephaly.

Gap type: unexplained_observation Source paper: Neuronal migration. (2001, Mech Dev, PMID:11429281)

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