What are the specific synaptic gene and protein changes caused by defective neurotransmitter release?

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Description

The abstract mentions that defective NT release generates consequences related to changed synaptic gene and protein activity but provides no details. Identifying these molecular changes is essential for understanding synaptopathy progression.

Gap type: unexplained_observation Source paper: Gene therapy targeting synaptopathy linked with Alzheimer’s and Parkinson’s disease. (2026, Neuroscience, PMID:41730496)

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