Why do cephalosporins achieve more reliable β-hemolytic streptococci eradication than penicillin?

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Description

The guideline states cephalosporins provide ‘more reliable eradication’ than first-line penicillin but doesn’t explain the mechanism. Understanding this could optimize antibiotic selection and improve treatment outcomes for recurrent cases.

Gap type: unexplained_observation Source paper: Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. (2016, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, PMID:26755048)

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