Why do ASOs offer 'enhanced effects over alternative therapeutics' for AD treatment?

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Priority

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Importance

75%

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85%

Market price

50%

Description

The abstract claims ASOs provide superior therapeutic effects compared to other approaches but doesn’t explain the underlying mechanisms responsible for this advantage. Understanding this could inform broader therapeutic strategy selection.

Gap type: unexplained_observation Source paper: Antisense oligonucleotides for Alzheimer’s disease therapy: from the mRNA to miRNA paradigm. (2021, EBioMedicine, PMID:34773891)

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