How do CC2D1A's diverse cellular roles (nuclear, mitochondrial, vesicular) mechanistically converge to cause ID/ASD?

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Description

The study reveals CC2D1A has pleiotropic functions across multiple cellular compartments, but the mechanistic link between these diverse roles and neurodevelopmental phenotypes remains unexplained. Understanding this convergence is critical for therapeutic targeting.

Gap type: unexplained_observation Source paper: Interactome Analysis of the CC2D1A Scaffold Reveals Novel Neuronal Interactions and a Postsynaptic Role. (None, None, PMID:40667103)

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