What molecular mechanisms link LXRβ to oligodendrocyte maturation and gene expression regulation?

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Description

The abstract shows LXRβ absence reduces expression of MCT1, BDNF, HMGCR, and GS in oligodendrocytes, but the direct transcriptional or signaling pathways are not explained. Understanding this mechanism is crucial for developing targeted therapies for motor neuron diseases.

Gap type: unexplained_observation Source paper: Role of LXRβ in oligodendrocytes in neuronal survival. (None, None, PMID:41034505)

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