What are the relative contributions of capillaries versus arterioles to overall blood flow regulation?

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Description

The authors explicitly state this remains unclear despite showing capillaries actively regulate blood flow independent of arterioles. This fundamental question impacts our understanding of cerebrovascular control and potential therapeutic targets for stroke and vascular dementia.

Gap type: open_question Source paper: Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina. (None, None, PMID:27605617)

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