What molecular mechanisms mediate translational control of Period2 by physiological temperature fluctuations?

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Description

The abstract reveals that subtle circadian temperature changes affect Period2 translational efficiency, challenging the dogma that circadian clocks operate solely through transcriptional/post-translational mechanisms. The specific molecular machinery linking temperature sensing to translational control remains unexplained.

Gap type: unexplained_observation Source paper: Roles of Temperature and Reactive Oxygen Species in Circadian Rhythms and Thermosensitivity. (2026, Biological & pharmaceutical bulletin, PMID:41922265)

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