What are the optimal mitochondrial targets and intervention strategies for enhancing adult neurogenesis in cognitive and mood disorders?

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Description

The abstract suggests targeting mitochondrial function for stem cell-based interventions but doesn’t specify which mitochondrial pathways or intervention approaches would be most effective. This represents a critical translational gap between mechanistic understanding and therapeutic application.

Gap type: open_question Source paper: Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain. (2021, International journal of molecular sciences, PMID:33805219)

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