What biological mechanisms drive aggressive behavior in the subset of treatment-resistant meningiomas?

neuro-oncology open
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Description

While most meningiomas are nonmalignant, a subset exhibits aggressive behavior with treatment resistance leading to significant morbidity. The underlying biological drivers of this aggressive phenotype remain poorly understood, limiting targeted therapeutic development.

Gap type: unexplained_observation Source paper: Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients. (None, None, PMID:38695575)

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