How do complement receptor structural features mechanistically drive neuroinflammation in neurodegeneration?

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Description

The abstract identifies complement as an etiological factor in many diseases but highlights gray areas in receptor structural biology. Understanding these structural-functional relationships is critical for developing targeted neuroinflammation therapies in neurodegenerative diseases.

Gap type: open_question Source paper: Structural biology of complement receptors. (None, None, PMID:37753090)

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