What structural mechanisms govern complement receptor cross-talk between innate and adaptive immunity in the CNS?

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Description

The authors note that complement receptors coordinate complex cross-talk between immune systems, but structural mechanisms remain unclear. This knowledge gap limits understanding of how peripheral immune dysfunction propagates to CNS neurodegeneration.

Gap type: open_question Source paper: Structural biology of complement receptors. (None, None, PMID:37753090)

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