What obstacles prevent EV-based treatments from progressing to clinical trials despite safety approval?

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Description

The abstract mentions that ‘some obstacles remain that prevent their progression into clinics’ despite EVs being deemed safe for human use. Identifying these specific barriers is essential for advancing promising EV therapeutics to patients with neurodegenerative diseases.

Gap type: open_question Source paper: Therapeutic potential of extracellular vesicles in neurodegenerative disorders. (2023, Handbook of clinical neurology, PMID:36803815)

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