Do other high-confidence autism genes beyond the five tested also disrupt enteric neuron development?

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Description

While the study tested 5 of 16 autism genes and found consistent migration defects, it remains unknown whether this phenotype generalizes to other high-confidence autism genes. This knowledge gap limits understanding of how broadly enteric neuron dysfunction contributes to autism-associated GI symptoms.

Gap type: open_question Source paper: Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility. (None, None, PMID:40050271)

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