Which non-microglial cell types mediate β-adrenergic effects on AD neuroinflammation?

neuroinflammation open
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Description

The authors suggest that adrenergic receptors on cell types other than microglia (such as astrocytes) may mediate disease-modifying effects, but this remains unproven. Identifying these cellular targets is essential for therapeutic development.

Gap type: open_question Source paper: Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease. (2024, Journal of neuroinflammation, PMID:39696597)

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