How do autophagy-dependent quality-control pathways regulate microglial proteostasis and function?

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Description

The abstract mentions context-dependent roles of autophagy in microglial function and identifies dissecting autophagy-dependent quality-control pathways as a priority area. The specific mechanisms linking autophagy to microglial proteostasis remain unclear.

Gap type: open_question Source paper: Microglia at the Forefront: New Insights From the Glial Club South Cone Meeting 2025. (2026, J Neurochem, PMID:41668347)

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