How does Ronin mechanistically assemble multiple promoters to form functional regulatory complexes?

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Description

The abstract describes Ronin’s ability to assemble promoters of housekeeping genes but doesn’t explain the molecular mechanism. Understanding this process is crucial since dysregulation of housekeeping gene expression contributes to neurodegeneration and metabolic dysfunction in brain aging.

Gap type: unexplained_observation Source paper: Regulatory architecture of housekeeping genes is driven by promoter assemblies. (None, None, PMID:37182209)

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