Why does DON increase BLA-PrL connectivity while simultaneously reducing excitatory transmission in PrL?

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Description

The abstract reports DON increases connectivity between BLA and PrL glutamatergic neurons, yet also diminishes excitatory synaptic transmission in PrL. This apparent contradiction suggests complex circuit-level compensatory mechanisms that remain unexplained and could inform therapeutic targeting.

Gap type: contradiction Source paper: Memory impairment mediated by deoxynivalenol via the BLA-PrL circuit. (None, None, PMID:40651373)

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