Why does age versus neuropathology differentially determine COVID-19 vulnerability in neurodegenerative versus neuroimmune diseases?

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Description

The authors hypothesize that age is decisive in neurodegenerative diseases while neuropathology is critical in neuroimmunological diseases for COVID-19 susceptibility, but the biological basis for this differential vulnerability remains unexplained. This could inform risk stratification and protective strategies.

Gap type: unexplained_observation Source paper: COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable? (2021, Journal of neurology, PMID:32696341)

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