Can lithium's anti-aging effects extend beyond kidney to other organ systems via GSK3β inhibition?

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Description

The abstract demonstrates lithium’s efficacy in delaying kidney aging through GSK3β inhibition, but whether this mechanism translates to systemic anti-aging effects across multiple organs remains unexplored. This has major implications for aging intervention strategies.

Gap type: open_question Source paper: Age-related GSK3β overexpression drives podocyte senescence and glomerular aging. (None, None, PMID:35166234)

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