What precise pathophysiological mechanisms link interneuron dysfunction to cognitive impairment in autism?

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Description

While the review establishes interneuron dysfunction occurs in syndromic autism with cognitive impairment, the specific causal mechanisms remain undefined. This knowledge gap limits development of targeted cognitive interventions.

Gap type: open_question Source paper: Interneuron Dysfunction in Syndromic Autism: Recent Advances. (2015, Developmental neuroscience, PMID:26183392)

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