What are the 'unexpected actions of HCN channels in the brain' referenced but not characterized in this study?

epilepsy/channelopathy open
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Description

The authors explicitly mention ‘unexpected actions of CHCNs in the brain’ but provide no details about these novel functions. Characterizing these unknown HCN roles could reveal new therapeutic targets for epilepsy treatment.

Gap type: open_question Source paper: Gene expression of the HCN family in rats with pilocarpine-induced epilepsy and in human hippocampal and cortical tissue. (2026, Brain research, PMID:41903877)

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