What are the detailed regulatory mechanisms controlling ferroptosis pathways in breast cancer cells?

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Description

The authors explicitly state that future research needs to make breakthroughs in understanding ferroptosis regulatory mechanisms. While multiple pathways (GSH-GPX4, FSP1-CoQ1, etc.) are mentioned, the specific control mechanisms remain unclear, limiting therapeutic targeting precision.

Gap type: open_question Source paper: Broadening horizons: the multifaceted role of ferroptosis in breast cancer. (2024, Frontiers in immunology, PMID:39664391)

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