Can noninvasive visual stimulation actually induce artificial sharp-wave-ripples in human hippocampus?

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Description

The authors propose using high-frequency visual stimulation to artificially induce sharp-wave-ripples, but provide no evidence this is feasible. Visual cortex stimulation reaching hippocampal circuits would require demonstrating cross-regional entrainment mechanisms that remain unproven.

Gap type: open_question Source paper: Artificial sharp-wave-ripples to support memory and counter neurodegeneration. (2024, Brain research, PMID:37871674)

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