How do functional amyloids like SST influence pathological amyloid aggregation in vivo?

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Description

The abstract suggests functional and disease-associated amyloids can mutually influence aggregation, but the physiological relevance and mechanisms in living brain tissue remain unclear. This gap is crucial for understanding whether functional amyloids protect against or promote pathological aggregation.

Gap type: open_question Source paper: Functional Amyloids and their Possible Influence on Alzheimer Disease. (2017, Discoveries (Craiova, Romania), PMID:32309597)

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