How do microglial activation states beyond M1/M2 respond to gut-derived metabolites in AD pathology?

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Description

The skeptic noted that M1/M2 classification is oversimplified, but the debate didn’t address how diverse microglial phenotypes actually respond to gut metabolites. Understanding this heterogeneity is essential for targeted neuroinflammation therapies.

Source: Debate session sess_gut-brain-ad (Analysis: gut-brain-ad)

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