How can DNMT inhibitors achieve brain-region specificity without systemic genomic instability?

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Description

The Theorist proposed targeted demethylation while the Skeptic raised serious safety concerns about carcinogenicity and global genomic disruption. No delivery mechanism or selectivity approach was established to resolve this technical barrier.

Source: Debate session sess_sda-2026-04-01-gap-v2-bc5f270e (Analysis: sda-2026-04-01-gap-v2-bc5f270e)

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