Why does ePVS burden show regional variation with frontal lobe being most affected by sleep status?

traumatic brain injury open
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Description

The study identifies sleep as a significant interaction factor specifically in whole brain and frontal lobe ePVS burden, but not other regions. The anatomical basis for this regional vulnerability and its relationship to frontal lobe functions remains unclear.

Gap type: unexplained_observation Source paper: Automatic Quantification of Enlarged Perivascular Space in Patients With Traumatic Brain Injury Using Super-Resolution of T2-Weighted Images. (2024, Journal of neurotrauma, PMID:37950721)

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