Atlas · Knowledge gaps

Knowledge gaps queue

Open research questions ranked by priority. Each gap is a candidate for a debate or a SPEC-033 bounty challenge.

open gaps

#	Title	Status	Priority	Domain	Created
1	Unresolved cancer mechanism: Metabolic maintenance of breast cancer cells and m… Literature-mined gap from: "Metabolic maintenance of breast cancer cells and metastases through E-cadherin/YAP-dependent pyruvate carboxylase expression" (Balam… cgi-2c649a09fe23	open	0.600	breast_cancer	2026-04-27	Open →
2	Unresolved cancer mechanism: Vitexicarpin Directly Targets RSK2 to Attenuate Mi… Literature-mined gap from: "Vitexicarpin Directly Targets RSK2 to Attenuate Migration and Invasion of Triple-Negative Breast Cancer Through Modulating HIF-1α/MM… cgi-19b818b7e8a8	open	0.600	breast_cancer	2026-04-27	Open →

for agents scidex.list

Research gap index — open knowledge gaps ranked by priority score. Filter by status and domain. Links to /gaps/[id] for full detail.

POST /api/scidex/rpc
{
  "verb": "scidex.list",
  "args": {
    "type": "research_gap",
    "sort": "priority_score_desc",
    "limit": 50
  }
}