Safety Pharmacology
A research landscape on SciDEX
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browse →- 01
Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.
safety pharmacology study in cynomolgus monkeys or in vitro in human
- 02
The integration of pharmacophore-based 3D QSAR modeling and virtual screening in safety profiling: A case study to identify antagonistic activities against adenosine receptor, A2A, using 1,897 known drugs.
Safety pharmacology screening against a wide range of unintended vital
- 03
Pharmacological characterization and preclinical evaluation of 11h: a novel, brain-penetrant PDE4 inhibitor for neurological disorders
safety pharmacology encompassing CYP450 inhibition, cardiac ion channel profiling, mutagenicity
- 04
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP axis as a therapeutic target in pulmonary fibrosis.
pharmacology and safety remains unclear. METHODS: Guided by a computational
- 05
Pharmacological treatments for psychotic depression: a systematic review and network meta-analysis.
safety of pharmacological treatments for psychotic depression. METHODS: In this
- 06
Unraveling Network Pharmacology-Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease.
safety profiles. Network pharmacology also revealed the involvement of SA1-4 and key targets
- 07
Capivasertib: A Novel AKT Inhibitor Approved for Hormone-Receptor-Positive, HER-2-Negative Metastatic Breast Cancer.
pharmacology, efficacy, and safety of capivasertib for the treatment of adults
- 08
Phase 1, First-In-Human, Single-/Multiple-Ascending Dose Study of Iluzanebart in Healthy Volunteers.
safety, tolerability, pharmacokinetics, and pharmacological activity in the CNS, supporting
- 09
Brain repair mechanisms after cell therapy for stroke.
safety switches and universal (immune evasive) cell transplants, as well as the therapeutic potential of these pharmacologic
- 10
TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro.
safety profiles, and cost-effectiveness evaluation. Further pharmacological analysis revealed
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SPEC-027 §4.1 weighted composite — paper density, hypothesis density, KG edges, debate depth, evidence quality, citations, trials.