What resolves this contention: Whether functional-similarity bias for E→E conne…

What resolves this contention: Whether functional-similarity bias for E→E connectivity exists specifically within mouse V1 L2/3: paired-recording studies find a clear like-to-like effect there, while the larger-N EM connectome does not detect one in that compartment. / In mouse V1 L2/3, in vitro paired recordings of in-vivo-characterised pyramidal neurons show connection probability scales with similarity of visual response tuning (functional like-to-like wiring). / MICrONS EM functional connectome reports widespread like-to-like wiring across mouse V1/RL but NO significant like-to-like effect within V1 L2/3 E→E projections specifically.