Version history
1 version on record. Newest first; the live version sits at the top with a live indicator.
- Live5/17/2026, 4:35:28 PM
bc8751b1add8Content snapshot
{ "field_tag": "neuroscience", "text": "What resolves this contention: {'position': 'PNNs primarily close plasticity by physically stabilizing PV synapses', 'evidence_description': 'ChABC restores OD plasticity; PNN formation correlates with critical period closure; structural stabilization of perisomatic synapses'} / {'position': 'PNNs close plasticity primarily through Otx2 accumulation in PV cells', 'evidence_description': 'Otx2 binds PNN sugars and accumulates in PV neurons; blocking Otx2-PNN interaction reopens plasticity; Otx2 conditional knockout prevents critical period closure'}", "source_refs": [ "wiki_page:computationreviewinhibitory-10", "wiki_page:computationreviewinhibitory-10", "wiki_page:computationreviewinhibitory-10" ], "importance": "0.7200", "tractability": "0.5500", "potential_impact": "0.7000", "composite_score": "0.2772", "elo_rating": "1500.00", "state": "open", "decay_rate": "0.01000", "resolution_evidence_refs": [] }