What resolves this contention: Disagreement on whether current experimental par…

What resolves this contention: Disagreement on whether current experimental paradigms can reliably detect ISN operation in cortex. Paper A finds clear evidence using optogenetic perturbation; Paper B argues that realistic network models show current perturbation methods are insufficient. / Inhibition stabilization is a widespread property of cortical networks, detectable across visual, somatosensory, and motor cortex even without sensory stimulation / Detecting ISN regime requires large-scale perturbation of the inhibitory population; results from reduced network models fail to predict responses in more realistic networks, implying existing experimental observations may be inconclusive