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- Live5/17/2026, 4:35:28 PM
89cb7e1a4823Content snapshot
{ "field_tag": "excitatory-recurrence", "text": "What resolves this contention: Disagreement over whether a like-to-like rule is sufficient to describe E→E connectivity/influence in mouse visual cortex. The connectomic (EM) analysis supports universal like-to-like, while large-scale all-optical perturbation finds a deep-L2/3 SST population that responds to diverse, non-like-tuned ensembles. / Our results reveal that neurons with similar response properties are preferentially connected within and across layers and areas-including feedback connections-supporting the universality of 'like-to-like' connectivity across the visual hierarchy. / Tracking population responses following delivery of precisely-defined widely-distributed activity patterns to the visual cortex of awake mice, we were surprised to identify neurons robustly responsive to stimulation of diverse ensembles, defying conventional like-to-like wiring rules.", "source_refs": [ "paper:paper-7ac22819c082", "paper:paper-8d923acf5f56", "wiki_page:computationalreviewrecurrence-03-paired-recording", "paper:paper-7ac22819c082", "paper:paper-8d923acf5f56", "wiki_page:computationalreviewrecurrence-03-paired-recording", "paper:paper-7ac22819c082", "paper:paper-8d923acf5f56", "wiki_page:computationalreviewrecurrence-03-paired-recording" ], "importance": "0.7200", "tractability": "0.5500", "potential_impact": "0.7000", "composite_score": "0.2772", "elo_rating": "1500.00", "state": "open", "decay_rate": "0.01000", "resolution_evidence_refs": [] }