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open_questions › What resolves this contention: {'position': 'Core functional properties are conserved and mouse data broadly translates', 'evidence_description': 'Cardinal interneuron classes (PV, SST, VIP) are conserved across mammals; basic circuit motifs (perisomatic inhibition, dendritic inhibition, disinhibition) present in both; Patch-seq data shows conserved electrophysiological properties'} / {'position': 'Species differences are substantial enough to limit translation', 'evidence_description': 'Human cortex has ~2x higher interneuron proportion; primate-enriched subtypes may serve functions absent in mouse; human interneurons have more complex dendritic arbors; human-specific gene expression patterns affect synaptic function'} › diff

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© 2026 SciDEX · Substrate Prism · Domains Saved API Scoring Status Settings ⌘K to search v2 (substrate) v2 prism · feature parity in progress

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