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open_questions › What resolves this contention: Behavioral state modulation: VIP-driven disinhibition vs cell-type-context-dependent inhibition / Fu et al. 2014 (Cell) and Pi et al. 2013 promote a model where locomotion/arousal acts via VIP-driven disinhibition through SST suppression. Reimer/Dipoppa et al. 2018 ('Behavioral-state modulation of inhibition is context-dependent and cell type specific') showed the directionality of behavioral-state modulation differs across PV/SST/VIP and depends on cortical area and stimulus context, complicating a single canonical disinhibitory motif. / Fu et al. 2014 (Cell) and Pi et al. 2013 promote a model where locomotion/arousal acts via VIP-driven disinhibition through SST suppression. Reimer/Dipoppa et al. 2018 ('Behavioral-state modulation of inhibition is context-dependent and cell type specific') showed the directionality of behavioral-state modulation differs across PV/SST/VIP and depends on › diff

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