What resolves this contention: Disease/target (ET-Vim vs PD-STN), trigger bioma…

What resolves this contention: Disease/target (ET-Vim vs PD-STN), trigger biomarker (movement vs theta phase) — Closed-loop strategies are biomarker- and target-specific. Beta-burst and movement-onset triggering benefit selected indications, but phase-locked stimulation can be detrimental. / Results Using the proposed method, stimulation was switched on for 80.37 ± 7.06% of the time when tremor‐evoking movements were present. / Motor improvement during open-loop, high-frequency DBS was accompanied by a reduction in the amount of cortical beta oscillations while akinetic and disturbed behavior during close-loop stimulation coincided with an increase in the amplitude of beta activity.