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What resolves this contention: Functional logic of local excitatory wiring in mouse V1: Ko 2011 reports a 'like-to-like' rule based on shared tuning, whereas the feature-binding model argues that the empirical responses to plaid stimuli are inconsistent with a pure like-to-like scheme and are better explained if excitatory subnetworks combine multiple feedforward features. / By comparing predictions from large scale computational models with in vivo recordings of visual representations in mouse V1, we found that responses to plaid stimuli were best explained by assuming feature binding connectivity. / Neurons with the same preference for oriented stimuli connected at twice the rate of neurons with orthogonal orientation preferences.
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May 16, 2026
Updated
May 17, 2026

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