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open_questions › What resolves this contention: ΔFosB accumulates uniquely in D1-MSNs and persists for weeks after drug cessation, functioning as a stable molecular switch that drives addiction-related gene expression changes / ΔFosB degradation kinetics may be faster than originally reported, and its accumulation pattern shows more cell-type heterogeneity than the D1-MSN-specific model suggests › diff

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