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What resolves this contention: Both papers parse BNST microcircuit valence, but emphasize different sub-nuclei as the primary anxiogenic vs anxiolytic substrate; they disagree on whether opposing valence is best mapped onto anterolateral vs oval BNST subdivisions or onto cell-type identity within shared subdivisions. / The anterior bed nucleus of the stria terminalis (BNST) has been recognized as a critical structure in regulating trait anxiety, contextual fear memory, and appetitive behavior, and is known to be sensitive to stress manipulations. / Early work stressed the differing involvement of the central amygdala (CeA) and bed nucleus of the stria terminalis (BNST) in the genesis of fear versus anxiety, respectively.
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May 16, 2026
Updated
May 17, 2026

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