Version history

{
  "field_tag": "astrocytes",
  "text": "What resolves this contention: Timescale of astrocyte Ca2+ responses to sensory/motor input. The earlier view (Paukert 2014) characterized astrocyte Ca2+ as strictly seconds-scale, whereas Stobart 2018 reports a distinct class of fast microdomains with hundreds-of-milliseconds onset that closely track neuronal responses. / Astrocyte Ca2+ transients in vivo occur on a >1 second timescale after locomotion or sensory events, reflecting slow biochemical steps to release Ca2+ from intracellular stores. / A substantial fraction of cortical astrocyte Ca2+ events occur on sub-second timescales (fast microdomains ~590 ms onset) that closely match neuronal response latencies, challenging the view that astrocyte Ca2+ is exclusively slow.",
  "source_refs": [
    "paper:paper-1b56aab49663",
    "paper:paper-23d7b31898ec",
    "wiki_page:computationalreviewastrocytes-09",
    "paper:paper-1b56aab49663",
    "paper:paper-23d7b31898ec",
    "wiki_page:computationalreviewastrocytes-09",
    "paper:paper-1b56aab49663",
    "paper:paper-23d7b31898ec",
    "wiki_page:computationalreviewastrocytes-09",
    "paper:paper-1b56aab49663",
    "paper:paper-23d7b31898ec",
    "wiki_page:computationalreviewastrocytes-09"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}