Version history

{
  "field_tag": "basal-ganglia",
  "text": "What resolves this contention: Functional anatomy of the ascending spiral: the original primate study inferred a tri-synaptic disinhibitory pathway, while intersectional genetic dissection in mouse finds connectivity present but topology incompatible with simple disinhibition. / Synaptic connectivity in the ascending striatonigrostriatal spiral exists, but the topology cannot support straightforward dorsomedial-to-dorsolateral disinhibition of dopamine signaling as Haber's spiral hypothesis predicted. / An ascending striato-nigro-striatal spiral connects ventral striatum to dorsolateral striatum via SNr-SNc disinhibition, providing a substrate for limbic-to-motor information flow during habit formation.",
  "source_refs": [
    "paper:paper-b3d499c61a02",
    "paper:paper-e0c1ebf94719",
    "wiki_page:computationalreviewloops-07",
    "paper:paper-b3d499c61a02",
    "paper:paper-e0c1ebf94719",
    "wiki_page:computationalreviewloops-07",
    "paper:paper-b3d499c61a02",
    "paper:paper-e0c1ebf94719",
    "wiki_page:computationalreviewloops-07"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}