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What resolves this contention: VIP boutons target only interneurons (canonical) vs target pyramidal cells / VIP→SST disinhibitory motif is the dominant connection (Pfeffer 2013, Pi 2013); VIP→Pyr small relative IPSC ratio / VIP boutons in deeper barrel cortex layers (L5/6) target excitatory pyramidal neurons (Sohn 2017 cercor/bhx220, Yu 2019)
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9914856a932b — 5/17/2026, 4:35:28 PM (live)
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9914856a932b — 5/17/2026, 4:35:28 PM (live)
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