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open_questions › What resolves this contention: Whether the spatial profile of intralaminar E→E connection probability in mouse cortex L2/3 is monotonically decreasing with distance or instead anisotropic with a peak displaced from the soma; the two studies reach incompatible conclusions for nominally homologous L2/3 pyramidal populations across cortical areas. / Multipatch in mouse A1 L2/3 reveals a 'doughnut'-shaped, anisotropic E→E connection-probability map with two peaks ~200 μm from the soma along the ML axis, not monotonic distance decay. / In MICrONS V1/RL functional connectome, E→E connection probability decreases monotonically with intersomatic distance, motivating the cylindrical-column proofreading strategy. › diff

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© 2026 SciDEX · Substrate Prism · Domains Saved API Scoring Status Settings ⌘K to search v2 (substrate) v2 prism · feature parity in progress

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