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  1. Live 67c4f5b3ec13
    5/17/2026, 4:35:28 PM
    Content snapshot
    {
      "field_tag": "neuroscience",
      "text": "What resolves this contention: {'position': 'Psychedelics act primarily through direct 5-HT2A activation on cortical pyramidal neurons', 'supporting_dois': ['10.1038/s41586-025-08813-6', '10.1016/j.taap.2025.117626', '10.1016/j.cub.2025.11.031', '10.1002/prp2.70238']} / {'position': 'Psychedelic effects require network-level disruption beyond single receptor activation', 'supporting_dois': ['10.21203/rs.3.rs-7099164/v1', '10.1002/prp2.70238', '10.1016/j.jad.2025.120335', '10.3389/fnins.2025.1606798', '10.1101/2025.03.05.641592']}",
      "source_refs": [
        "wiki_page:computationalreviewneuromodulation-06",
        "wiki_page:computationalreviewneuromodulation-06",
        "wiki_page:computationalreviewneuromodulation-06"
      ],
      "importance": "0.7200",
      "tractability": "0.5500",
      "potential_impact": "0.7000",
      "composite_score": "0.2772",
      "elo_rating": "1500.00",
      "state": "open",
      "decay_rate": "0.01000",
      "resolution_evidence_refs": []
    }