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What resolves this contention: Two complementary loci for stop-signal cancellation: Mallet et al. emphasize arkypallidal-to-striatum stopping (a slower, post-pause cancel step), whereas Schmidt et al. highlight a STN→SNr race that sets the point of no return. The two are not strictly contradictory but propose different anatomical bottlenecks for cancellation. / Stop responses are earlier and stronger in the Arky compared to the Proto subpopulation. / By contrast, neurons downstream in the substantia nigra pars reticulata (SNr) only responded to Stop cues in trials with successful cancellation.
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May 16, 2026
Updated
May 17, 2026

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