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What resolves this contention: Disagreement on whether ISN is uniform across cortical layers or shows a gradient with superficial layers being non-ISN / Layer 2/3 does not operate in the ISN regime, while layers 4 and 5 do, showing a gradient of inhibitory stabilization across cortical layers / ISN operation is found broadly across cortical areas even without sensory stimulation, with no strong evidence for layer-specific ISN/non-ISN boundaries
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f4fbb2f503c1 — 5/17/2026, 4:35:28 PM (live)
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f4fbb2f503c1 — 5/17/2026, 4:35:28 PM (live)
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